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Table 2 Mutant types observed in the k13 of imported P. falciparum infections

From: Molecular surveillance of Pfcrt and k13 propeller polymorphisms of imported Plasmodium falciparum cases to Zhejiang Province, China between 2016 and 2018

Codon position

Amino acid reference

Nucleotide reference

Amino acid mutation

Nucleotide mutation

Location and year (No.)

441

P

ACC

S

ATC

Nigeria 2017 (1)a, 2018 (1)b

464

D

GAT

E

GAA

Guinea 2018 (1)

469

C

TGC

C

TGT

Nigeria 2017 (1)

471

R

CGT

R

CGC

Angola 2016 (1)

478

T

ACC

T

ACG

Benin 2017 (1)

492

L

TTA

L

TTG

Ghana 2016 (1)

493

Y

TAC

Y

TAT

Liberia 2017 (1), Côte d’Ivoire 2018 (1)

496

G

GGT

G

GGC

Ghana 2018 (1)

503

K

AAG

E

GAG

Cameroon 2018 (1)

535

T

ACG

T

ACA

Côte d’Ivoire 2017 (1)

561

R

CGT

H

CAT

Rwanda 2017 (1), Myanmar 2017 (1)

578

A

GCT

S

TCT

Cameroon 2016 (1)

589

V

GTC

V

GTG

Nigeria 2016 (2)

622

R

AGA

I

ATA

Mozambique 2016 (1), Somalia 2016 (1)

638

G

GGA

G

GGG

Republic of Niger 2017 (1)

650

V

GTT

F

TTT

Nigeria 2016 (1)

664

N

AAT

N

AAC

Nigeria 2017 (1)

676

A

GCC

A

GCT

Nigeria 2016 (1), Guinea 2016 (1)

694

N

AAT

K

AAG

Côte d’Ivoire 2017 (1), Angola 2017 (1)

  1. No. number of isolates
  2. aIsolate with mutant type of Pfcrt
  3. bIsolate with mixed type of Pfcrt