Molecular surveillance of Pfcrt and k13 propeller polymorphisms of imported Plasmodium falciparum cases to Zhejiang Province, China between 2016 and 2018

Table 3 Genetic diversity of k13 gene from imported P. falciparum infections

Region	n	S	Hd (SD)	Pi(JC)	k	Tajima’s D	p-value^△
West Africa	247	15	0.141 (0.030)	0.0002	0.162	− 2.32586	< 0.01
South Africa	53	3	0.111 (0.059)	0.00014	0.113	− 1.68986	> 0.05
Central Africa	106	2	0.038 (0.026)	0.00005	0.038	− 1.37037	> 0.10
East Africa	21	2	0.186 (0.110)	0.00024	0.190	− 1.51414	> 0.10
Total^a	427	20	0.114 (0.021)	0.00016	0.126	− 2.38774	< 0.01

S number of segregating sites, Hd haplotype diversity, Pi (JC) nucleotide diversity (Jukes and Cantor), k average number of nucleotide differences
^aSequences from North Africa, Southeast Asia and Oceania were not included due to their limited sample size or number of mutants
^△p-value for Tajima’s D

ISSN: 1475-2875