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Table 2 Extent of and factors associated with having ever encountered ACT treatment failure among 685 healthcare professionals using Multivariate logistic regression

From: Healthcare professionals’ perspective can guide post-marketing surveillance of artemisinin-based combination therapy in Uganda

Category

Ever encountered ACT treatment failure

OR

CI

P-value

Yes, n (%)

No, n (%)

Overall

421 (61)

264 (39)

   

Region

     

 Western

50 (38)

80 (62)

1.0

 Central

184 (62%)

111 (38%)

3.0

1.7–5.2

0.0001

 Eastern

99 (77%)

29 (23%)

5.4

2.9–9.8

0.0001

 Northern

88 (67%)

44 (33%)

5.3

2.9–9.9

0.0001

Gender

     

 Male

214 (61%)

135 (39%)

1.0

 Female

207 (62%)

129 (38%)

0.8

0.6–1.2

0.311

Age category

     

 < 25

55 (49%)

47 (51%)

1.0

 25–34

267 (61%)

172 (31%)

0.9

0.5–1.4

0.538

 35 and above

99 (74%)

35 (26%)

1.1

0.5–2.5

0.734

Education level

     

 Certificate

129 (63%)

76 (37%)

1.0

 Diploma

165 (67%)

80 (33%)

0.9

0.5–1.6

0.775

 Bachelors or higher

127 (54%)

108 (46%)

1.0

0.5–1.9

0.973

Professional experience

     

 0–1 years

60 (39%)

92 (61%)

1.0

 2–3 years

129 (59%)

88 (41)

1.2

1.6–5.6

0.511

 4–5 years

104 (73%)

39 (27%)

2.4

2.2–10.2

0.003

 ≥ 6 years

128 (74%)

45 (26%)

3.2

1.6–11.4

0.001

Sector of practice

     

 Public

157 (57%)

119 (43%)

1.0

 Private

264 (65%)

145 (35%)

2.7

1.7–3.9

0.0001

Professional cadre

     

 Medical officer

58 (53%)

52 (47%)

1.0

 Pharmacist/Pharm tech

50 (54%)

42 (46%)

0.6

0.5–2.9

0.121

 Nurse

218 (65%)

116 (35%)

0.7

1.3–7.2

0.337

 Clinical officer

81 (71%)

33 (29%)

1.3

1.1–7.8

0.514

 Other

14 (40%)

21 (60%)

0.2

0.5–4.5

0.110

Malaria patients per day

     

 < 10 patients

223 (52%)

215 (48%)

1.0

 ≥ 10 patients

188 (79%)

49 (21%)

2.5

1.6–6.6

0.0001