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Table 3 Cox regression analysis showing determinants of recurrent malaria among children (< 5 years) treated with Alu. (n = 147)

From: Usefulness of day 7 lumefantrine plasma concentration as a predictor of malaria treatment outcome in under-fives children treated with artemether-lumefantrine in Tanzania

VariablescHRs (95% CI)p valueaHRs (95% CI)p value
Age (months)1 (0.98–1.05)0.461.3 (0.9–2.0)0.16
Weight (kg)1.1 (0.95–1.42)0.160.1 (0.0–1.4)0.09
WAZ1.7 (0.94–3.1)0.0831 (0.6–1577)0.09
MUAC1.4 (0.89–2.1)0.163 (1.1–8.2)0.029
Baseline temperature (℃)1.0 (0.64–1.7)0.851.0 (0.5–1.9)0.94
 Baseline parasitemia (g/dl)
 < 10000.0 (0.0–)0.980.0 (0.00–)0.96
 1000–10,0000.9 (0.2–3.2)0.830.7 (0.2–3.5)0.69
 ≥ 10,0001 1 
Sex
 Female0.7 (0.2–2.3)0.581.2 (0.3–5.2)0.82
 Male1   
Treatment arm
 Artefan®0.7 (0.2–2.1)0.470.5 (0.1–2.3)0.57
 Coartem®1 1 
Baseline hemoglobin (g/dl)1.2 (0.8–1.6)0.341.3 (0.8–2.0)0.24
 Day 7 plasma lumefantrine concentration (ng/ml) (n = 104)1.2 (0.24–5.9)0.831.3 (0.2–8.1)0.81