Table 3 Cox regression analysis showing determinants of recurrent malaria among children (< 5 years) treated with Alu. (n = 147)
Variables | cHRs (95% CI) | p value | aHRs (95% CI) | p value |
|---|---|---|---|---|
Age (months) | 1 (0.98–1.05) | 0.46 | 1.3 (0.9–2.0) | 0.16 |
Weight (kg) | 1.1 (0.95–1.42) | 0.16 | 0.1 (0.0–1.4) | 0.09 |
WAZ | 1.7 (0.94–3.1) | 0.08 | 31 (0.6–1577) | 0.09 |
MUAC | 1.4 (0.89–2.1) | 0.16 | 3 (1.1–8.2) | 0.029 |
Baseline temperature (℃) | 1.0 (0.64–1.7) | 0.85 | 1.0 (0.5–1.9) | 0.94 |
 Baseline parasitemia (g/dl) | ||||
 < 1000 | 0.0 (0.0–) | 0.98 | 0.0 (0.00–) | 0.96 |
 1000–10,000 | 0.9 (0.2–3.2) | 0.83 | 0.7 (0.2–3.5) | 0.69 |
 ≥ 10,000 | 1 |  | 1 |  |
Sex | ||||
 Female | 0.7 (0.2–2.3) | 0.58 | 1.2 (0.3–5.2) | 0.82 |
 Male | 1 |  |  |  |
Treatment arm | ||||
 Artefan® | 0.7 (0.2–2.1) | 0.47 | 0.5 (0.1–2.3) | 0.57 |
 Coartem® | 1 |  | 1 |  |
Baseline hemoglobin (g/dl) | 1.2 (0.8–1.6) | 0.34 | 1.3 (0.8–2.0) | 0.24 |
 Day 7 plasma lumefantrine concentration (ng/ml) (n = 104) | 1.2 (0.24–5.9) | 0.83 | 1.3 (0.2–8.1) | 0.81 |