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Table 4 Factors associated with adherence to ACTs among febrile children under-five who received treatment with an artemisinin-based combination (n = 466)

From: Factors associated with access and adherence to artemisinin‐based combination therapy (ACT) for children under five: a secondary analysis of a national survey in Sierra Leone

Variable n/N % Unadjusted analysis Adjusted analysis
OR (95% CI) p value OR (95% CI) p value
Location
 Rural 178/385 46.2% Ref 0.233 Ref 0.245
 Urban 44/81 55.3% 1.44 (0.79–2.64) 1.49 (0.76–2.95)
Region
 West 11/35 30.1% Ref 0.355 Ref 0.211
 North 98/202 47.9% 2.13 (0.83–5.50) 2.58 (0.99–6.77)
 South 60/124 49.3% 2.26 (0.87–5.89) 2.83 (1.04–7.68)
 East 53/105 50.8% 2.40 (0.91–6.32) 2.76 (1.04–7.32)
Household size
 1–5 63/144 45.3% Ref 0.487 Ref 0.620
 6–10 122/256 47.3% 1.08 (0.72–1.62) 1.13 (0.73–1.73)
 11 + 37/66 54.2% 1.43 (0.79–2.59) 1.35 (0.73–2.50)
Household religion
  Muslim 172/373 46.0% Ref 0.158 Ref 0.058
 Christian 50/93 54.7% 1.42 (0.87–2.30) 1.61 (0.98–2.65)
Socio-economic status
 1 (poorest) 62/131 46.5% Ref 0.883 Ref 0.930
 2 83/175 47.0% 1.02 (0.64–1.63) 1.07 (0.66–1.75)
 3 (least poor) 77/160 49.4% 1.13 (0.68–1.86) 1.12 (0.60–2.08)
Respondent education
 None 138/288 48.1% Ref 0.984 Ref 0.854
 Primary 30/63 48.5% 1.02 (0.58–1.80) 0.87 (0.46–1.64)
 Secondary or higher 50/106 46.5% 0.94 (0.57–1.54) 0.80 (0.46–1.38)
  Arabic or other 4/9 42.3% 0.79 (0.18–3.49) 0.74 (0.17–3.26)
Know everyone is at risk
 No 60/120 51.3% Ref 0.390 Ref 0.329
 Yes 162/346 46.4% 0.82 (0.53–1.29) 0.79 (0.49–1.27)
Know ITNs protect
 No 62/128 48.4% Ref 0.844 Ref 0.943
 Yes 160/338 47.4% 0.96 (0.63–1.47) 0.98 (0.63–1.54)
U5 slept under ITN
 No 58/118 48.8% Ref 0.779 Ref 0.829
 Yes 164/348 47.3% 0.94 (0.61–1.44) 0.95 (0.60–1.50)
Knowledge ACTs
 No 88/187 46.9% Ref 0.805 Ref 0.866
 Yes 134/279 48.2% 1.05 (0.70–1.57) 1.04 (0.67–1.60)
Child age (months)
 0–23 months 60/135 43.9% Ref 0.276 Ref 0.270
 24–59 months 162/331 49.2% 1.24 (0.84–1.81) 1.26 (0.83–1.90)
Prompt treatment (< 24 h)
 No 102/207 49.5% Ref 0.744 Ref 0.150
 Yes 119/258 45.9% 1.05 (0.79–1.39) 1.25 (0.92–1.70)
Public health facility
 No 28/57 48.3% Ref 0.926 Ref 0.951
 Yes 194/409 47.6% 0.97 (0.55–1.74) 0.98 (0.53–1.81)
ACT within 24 h
 No 85/154 55.0% Ref 0.047 Ref 0.015
 Yes 137/312 44.1% 0.65 (0.42–0.99) 0.55 (0.34–0.89)
  1. Data for ACT duration was available for 466 children out of the 469 that received ACT