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Table 4 Factors associated with adherence to ACTs among febrile children under-five who received treatment with an artemisinin-based combination (n = 466)

From: Factors associated with access and adherence to artemisinin‐based combination therapy (ACT) for children under five: a secondary analysis of a national survey in Sierra Leone

Variable

n/N

%

Unadjusted analysis

Adjusted analysis

OR (95% CI)

p value

OR (95% CI)

p value

Location

 Rural

178/385

46.2%

Ref

0.233

Ref

0.245

 Urban

44/81

55.3%

1.44 (0.79–2.64)

1.49 (0.76–2.95)

Region

 West

11/35

30.1%

Ref

0.355

Ref

0.211

 North

98/202

47.9%

2.13 (0.83–5.50)

2.58 (0.99–6.77)

 South

60/124

49.3%

2.26 (0.87–5.89)

2.83 (1.04–7.68)

 East

53/105

50.8%

2.40 (0.91–6.32)

2.76 (1.04–7.32)

Household size

 1–5

63/144

45.3%

Ref

0.487

Ref

0.620

 6–10

122/256

47.3%

1.08 (0.72–1.62)

1.13 (0.73–1.73)

 11 +

37/66

54.2%

1.43 (0.79–2.59)

1.35 (0.73–2.50)

Household religion

  Muslim

172/373

46.0%

Ref

0.158

Ref

0.058

 Christian

50/93

54.7%

1.42 (0.87–2.30)

1.61 (0.98–2.65)

Socio-economic status

 1 (poorest)

62/131

46.5%

Ref

0.883

Ref

0.930

 2

83/175

47.0%

1.02 (0.64–1.63)

1.07 (0.66–1.75)

 3 (least poor)

77/160

49.4%

1.13 (0.68–1.86)

1.12 (0.60–2.08)

Respondent education

 None

138/288

48.1%

Ref

0.984

Ref

0.854

 Primary

30/63

48.5%

1.02 (0.58–1.80)

0.87 (0.46–1.64)

 Secondary or higher

50/106

46.5%

0.94 (0.57–1.54)

0.80 (0.46–1.38)

  Arabic or other

4/9

42.3%

0.79 (0.18–3.49)

0.74 (0.17–3.26)

Know everyone is at risk

 No

60/120

51.3%

Ref

0.390

Ref

0.329

 Yes

162/346

46.4%

0.82 (0.53–1.29)

0.79 (0.49–1.27)

Know ITNs protect

 No

62/128

48.4%

Ref

0.844

Ref

0.943

 Yes

160/338

47.4%

0.96 (0.63–1.47)

0.98 (0.63–1.54)

U5 slept under ITN

 No

58/118

48.8%

Ref

0.779

Ref

0.829

 Yes

164/348

47.3%

0.94 (0.61–1.44)

0.95 (0.60–1.50)

Knowledge ACTs

 No

88/187

46.9%

Ref

0.805

Ref

0.866

 Yes

134/279

48.2%

1.05 (0.70–1.57)

1.04 (0.67–1.60)

Child age (months)

 0–23 months

60/135

43.9%

Ref

0.276

Ref

0.270

 24–59 months

162/331

49.2%

1.24 (0.84–1.81)

1.26 (0.83–1.90)

Prompt treatment (< 24 h)

 No

102/207

49.5%

Ref

0.744

Ref

0.150

 Yes

119/258

45.9%

1.05 (0.79–1.39)

1.25 (0.92–1.70)

Public health facility

 No

28/57

48.3%

Ref

0.926

Ref

0.951

 Yes

194/409

47.6%

0.97 (0.55–1.74)

0.98 (0.53–1.81)

ACT within 24 h

 No

85/154

55.0%

Ref

0.047

Ref

0.015

 Yes

137/312

44.1%

0.65 (0.42–0.99)

0.55 (0.34–0.89)

  1. Data for ACT duration was available for 466 children out of the 469 that received ACT