Table 2 Crude association between hepatic adverse events and episodes groups over treatment arms
| Episodes groups | COR (95% CI) with hepatic adverse events | |||||
|---|---|---|---|---|---|---|
| Elevated ALT | Elevated AST | Elevated ALP | Elevated direct bilirubin | Elevated total bilirubin | ||
| AL | First treatment | 1 | 1 | 1 | 1 | 1 |
| Retreatment |
0.25 (0.08; 0.72) * |
0.18 (0.07;0.45) *** |
2.09 (0.58; 7.58) |
1.80 (0.99; 3.30) |
2.13 (1.15; 3.92) * | |
| PA | First treatment | 1 | 1 | 1 | 1 | 1 |
| Retreatment |
0.33 (0.14; 0.76) * |
0.65 (0.28; 1.53) |
1.17 (0.33; 4.04) |
1.66 (0.83; 3.34) |
1.36 (0.71; 2.60) | |