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Table 1 Summary of alleles observed in Pfdhfr and Pfdhps genes

From: Low prevalence of highly sulfadoxine‐resistant dihydropteroate synthase alleles in Plasmodium falciparum isolates in Benin

Pfdhfr Klouékanmey
n = 79 (%)
Djougou
n = 90 (%)
Overall
n = 169 (%)
C50 79 (100) 90 (100) 169 (100)
50R 0 0 0
50 C/R 0 0 0
N51 3 (3.8) 13 (14.4) 16 (9.5)
51I 72 (91.1) 74 (82.3) 146 (86.4)
51 N/I 4 (5.1) 3 (3.3) 7 (4.1)
C59 1 (1.3) 5 (5.6) 6 (3.6)
59R 72 (91.1) 80 (88.8) 152 (89.9)
59 C/R 6 (7.6) 5 (5.6) 11 (6.5)
S108 0 5 (5.6) 5 (3.0)
108 N 78 (98.7) 82 (91.1) 160 (94.7)
108S/N 1 (1.3) 3 (3.3) 4 (2.4)
I164 79 (100) 90 (100) 169 (100)
164L 0 0 0
164I/L 0 0 0
Pfdhps Klouékanmey
n = 68 (%)
Djougou
n = 85 (%)
Overall
n = 153 (%)
I431 65 (95.6) 82 (96.4) 147 (96.1)
431V 3 (4.4) 1 (1.2) 4 (2.6)
431I/V 0 2 (2.4) 2 (1.3)
S436 41 (60.2) 40 (47.1) 81 (52.9)
436A 22 (32.4) 32 (37.6) 54 (35.3)
436S/A 5 (7.4) 13 (15.3) 18 (11.8)
A437 0 4 (4.7) 4 (2.6)
437G 68 (100) 77 (90.6) 145 (94.8)
437A/G 0 4 (4.7) 4 (2.6)
K540 66 (97.0) 83 (97.6) 149 (97.4)
540E 1 (1.5) 1 (1.2) 2 (1.3)
540K/E 1 (1.5) 1 (1.2) 2 (1.3)
A581 65 (95.6) 84 (98.8) 149 (97.4)
581G 3 (4.4) 1 (1.2) 4 (2.6)
581A/G 0 0 0
A613 65 (95.6) 81 (95.3) 146 (95.4)
613S 3 (4.4) 3 (3.5) 6 (3.9)
613A/S 0 1 (1.2) 1 (0.7)
  1. Bold letters denote mutant alleles
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