Table 1 Summary of alleles observed in Pfdhfr and Pfdhps genes
Pfdhfr | Klouékanmey n = 79 (%) | Djougou n = 90 (%) | Overall n = 169 (%) |
|---|---|---|---|
C50 | 79 (100) | 90 (100) | 169 (100) |
50R | 0 | 0 | 0 |
50 C/R | 0 | 0 | 0 |
N51 | 3 (3.8) | 13 (14.4) | 16 (9.5) |
51I | 72 (91.1) | 74 (82.3) | 146 (86.4) |
51 N/I | 4 (5.1) | 3 (3.3) | 7 (4.1) |
C59 | 1 (1.3) | 5 (5.6) | 6 (3.6) |
59R | 72 (91.1) | 80 (88.8) | 152 (89.9) |
59 C/R | 6 (7.6) | 5 (5.6) | 11 (6.5) |
S108 | 0 | 5 (5.6) | 5 (3.0) |
108 N | 78 (98.7) | 82 (91.1) | 160 (94.7) |
108S/N | 1 (1.3) | 3 (3.3) | 4 (2.4) |
I164 | 79 (100) | 90 (100) | 169 (100) |
164L | 0 | 0 | 0 |
164I/L | 0 | 0 | 0 |
Pfdhps | Klouékanmey n = 68 (%) | Djougou n = 85 (%) | Overall n = 153 (%) |
|---|---|---|---|
I431 | 65 (95.6) | 82 (96.4) | 147 (96.1) |
431V | 3 (4.4) | 1 (1.2) | 4 (2.6) |
431I/V | 0 | 2 (2.4) | 2 (1.3) |
S436 | 41 (60.2) | 40 (47.1) | 81 (52.9) |
436A | 22 (32.4) | 32 (37.6) | 54 (35.3) |
436S/A | 5 (7.4) | 13 (15.3) | 18 (11.8) |
A437 | 0 | 4 (4.7) | 4 (2.6) |
437G | 68 (100) | 77 (90.6) | 145 (94.8) |
437A/G | 0 | 4 (4.7) | 4 (2.6) |
K540 | 66 (97.0) | 83 (97.6) | 149 (97.4) |
540E | 1 (1.5) | 1 (1.2) | 2 (1.3) |
540K/E | 1 (1.5) | 1 (1.2) | 2 (1.3) |
A581 | 65 (95.6) | 84 (98.8) | 149 (97.4) |
581G | 3 (4.4) | 1 (1.2) | 4 (2.6) |
581A/G | 0 | 0 | 0 |
A613 | 65 (95.6) | 81 (95.3) | 146 (95.4) |
613S | 3 (4.4) | 3 (3.5) | 6 (3.9) |
613A/S | 0 | 1 (1.2) | 1 (0.7) |