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Table 2 CYP2C8 genotype frequencies by treatment outcome after treatment with artesunate–amodiaquine

From: Influence of cytochrome P450 (CYP) 2C8 polymorphisms on the efficacy and tolerability of artesunate‐amodiaquine treatment of uncomplicated Plasmodium falciparum malaria in Zanzibar

Treatment outcome *1/*1 *2 carriers *3 carriers Total
ACPR; % (n) 63.3 (124) 31.1 (61) 5.6 (11) 100 (196)
Recurrent infections; % (n) 56.4 (75) 38.4 (51) 5.3 (7) 100 (133)
Re-infections; % (n) 55.9 (52) 37.6 (35) 6.5 (6) 100 (93)
Recrudescences; % (n) 51.7 (15) 44.8 (13) 3.5 (1) 100 (29)
Recurrent infections IA; % (n) 72.7 (8) 27.3 (3) 0.0 (0) 100 (11)
  1. Relative (%) and absolute (n) genotype frequencies by treatment outcome among children under 5 years old with uncomplicated falciparum malaria in Zanzibar
  2. ACPR adequate clinical and parasitological response, IA Inconclusive analysis