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Table 2 CYP2C8 genotype frequencies by treatment outcome after treatment with artesunate–amodiaquine

From: Influence of cytochrome P450 (CYP) 2C8 polymorphisms on the efficacy and tolerability of artesunate‐amodiaquine treatment of uncomplicated Plasmodium falciparum malaria in Zanzibar

Treatment outcome

*1/*1

*2 carriers

*3 carriers

Total

ACPR; % (n)

63.3 (124)

31.1 (61)

5.6 (11)

100 (196)

Recurrent infections; % (n)

56.4 (75)

38.4 (51)

5.3 (7)

100 (133)

Re-infections; % (n)

55.9 (52)

37.6 (35)

6.5 (6)

100 (93)

Recrudescences; % (n)

51.7 (15)

44.8 (13)

3.5 (1)

100 (29)

Recurrent infections IA; % (n)

72.7 (8)

27.3 (3)

0.0 (0)

100 (11)

  1. Relative (%) and absolute (n) genotype frequencies by treatment outcome among children under 5 years old with uncomplicated falciparum malaria in Zanzibar
  2. ACPR adequate clinical and parasitological response, IA Inconclusive analysis