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Fig. 1 | Malaria Journal

Fig. 1

From: Diversity-oriented synthesis derived indole based spiro and fused small molecules kills artemisinin-resistant Plasmodium falciparum

Fig. 1

Screening of DOS-synthesised compounds for anti-plasmodial activity. a Synchronized parasite culture in ring stage were seeded to adjust parasitaemia to 1%. This synchronized culture was then treated either with DMSO or compounds (5 µM) for 48 h. Giemsa-stained slides were prepared at 0 and 48 h post-treatment to monitor the parasitaemia. Graphs were prepared for the average value of three independent experiments performed in duplicate with ± SD. b Parasites at different stages of the IDC at 0 and 48 h post-treatment were calculated. Table shows the percentage of remaining parasites in different stages of IDC from three independent experiments with ± SD

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