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Fig. 3 | Malaria Journal

Fig. 3

From: Diversity-oriented synthesis derived indole based spiro and fused small molecules kills artemisinin-resistant Plasmodium falciparum

Fig. 3

Compounds 2 and 3 enhance ROS generation in Plasmodium. Parasites were treated with DMSO or compounds 2 or 3 for 48 h followed by H2DCFDA dye staining. Signal was detected using fluorescence microscope. DAPI was used to stain the parasite nucleus. Graph was plotted for relative intensity of H2DCFDA dye signal. P value (0.005) shows significant enhancement in ROS generation

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