Rank | Research questions | Justifications |
---|---|---|
Gouvernance | ||
3 | What is the most effective strategy (door-to-door, cluster sites…) for seasonal malaria chemo-prevention? | There is a need to find adequate strategies for a good implementation of SMC campaigns, taking into account local constraints |
5 | What is the quality of malaria management at different levels of the health system? | The insufficient quality data on the management of malaria in health facilities and poor estimation of malaria cases, is often a challenge for decision making for planning and implantation |
14 | What part NICT (new information and communication technology) has in the management of quality data? | Due to the low level of completeness, promptitude and archiving, there is need to look into the use of technology |
17 | What system of collaboration should be put in place between Ministry of Health and other partners? | Insufficient coordination of activities have been recorded across the board |
Human resources | ||
2 | What is the contribution of Community Drug Distributors in the management of severe malaria cases in children under five years of age as part of pre-transfer treatment? | There is often inadequate treatment (pre-transfer treatment) of severe malaria before the transfer to better facility. This delays treatment on arrival and recovery |
16 | Can CHWs contribute to improving the supervised administration of IPT-2 and IPT-3? | There is a need to know how programmes can improve the low coverage of IPT-2 and IPT-3 |
Drug/malaria medicines | ||
4 | How effective and tolerable is ACT (artemisinin-based combination therapy) under actual conditions of use? | More data are needed on the efficacy and tolerability of ACT under actual conditions of use |
6 | What are the adverse effects of anti-malarial drugs (artemisinin-based combination, SP-AQ) | More data are needed on the pharmacovigilance of anti-malarial drugs in mass drug distribution: toxicological effects especially hepatic |
13 | How effective are the medicines used in traditional medicine in the of malaria case management at the community level? | The high use of traditional medicine by the population and the low collaboration between traditional and modern medicine should be explored |
21 | What is the comparative advantage of the dihydroartemisinin (DHA)-piperazine combination over SP-AQ? | Due to its side effects and limitations, programmes should look also for an alternative to SP-AQ as part of the SMC |
Service | ||
11 | What is the quality of the supply/commodities? | There are counterfeit medicines in circulation, leading to treatment failure and difficult diagnosis |
10 | What is the performance of input supply chain systems? | Commodities stock-outs, insufficient rational management of medicines, are often recorded |
Prevention | ||
7 | How effective are insecticides in long-lasting insecticidal nets (LLINs) in vector control? | After few years of use, there is a lack of updated efficacy data on insecticides used in LLINs |
9 | What are the factors for non-use of LLINs in vector control? | Managers and health workers have noticed a low level of public support for the use of LLINs |
18 | What is the level of use and effectiveness of indoor residual spraying for malaria prevention at the community level? | There are insufficient data on its IRS efficiency |
19 | How effective is the mosquito repellent soap developed in Burkina Faso as part of a multicenter study? | Research should contribute to find new alternative means of prevention to LLINs |
20 | What is the feasibility and effectiveness of impregnating nets with two insecticides? | With few years of the current tools, there is a need to develop of new means or tool of vector control in order to limit the spread of resistance of malaria vectors |
Monitoring and evaluation | ||
1 | What are the factors that influence adherence to day 2 and day 3 doses during SMC? | The effectiveness of the ongoing strategy is not fully documented leading to insufficient data and monitoring of compliance with 2nd and 3rd doses in the community |
12 | What is the diagnostic performance of RDTs at the facility level? | Little is known about the performance of real-world/real-time RDTs (rapid diagnostic test) |
15 | What is the level of morbidity and mortality attributable to malaria? | There is a need to evaluate the impact of control programmes |
Populations adherence/buy-in | ||
8 | What are the communication channels, supports and strategies that induce the most behavior change? | Behavioral change at community and individual level has been slow |