Skip to main content

Table 6 Comparison of CNV in KIR genes in populations with historically varied malaria transmission intensity

From: Diversity of KIR genes and their HLA-C ligands in Ugandan populations with historically varied malaria transmission intensity

 

Tororo

Jinja

Kanungu

p-value

N = 438

F (%)

N = 414

F (%)

N = 446

F (%)

KIR2DL1 CNV

 0

6

1.4

5

1.2

5

1.2

0.985

 1

104

23.7

99

23.9

101

22.6

 2

328

74.9

310

74.9

340

76.2

KIR2DL2 CNV

 0

184

42

174

42

192

43.1

0.834

 1

220

50.2

199

48.1

216

48.4

 2

34

7.8

41

9.9

38

8.5

KIR2DL3 CNV

 0

72

16.4

62

15

66

14.8

0.195

 1

154

35.2

171

41.3

191

42.8

 2

212

48.4

181

43.7

189

42.4

KIR2DS2 CNV

 0

214

48.8

196

47.3

218

48.9

0.387

 1

207

47.3

189

45.7

204

45.7

 2

17

3.9

29

7

24

5.4

KIR2DS5 CNV

 0

336

76.7

324

78.3

372

83.4

0.144

 1

98

22.3

86

20.7

71

16

 2

4

1

4

1

3

0.6

KIR2DL5 CNV

 0

292

66.8

282

68.2

318

71.4

0.650

 1

138

31.4

126

30.5

121

27

 2

8

1.8

6

1.3

7

1.6

  1. CNV is copy number variation of KIR genes. The value can be 0, 1 or 2 in these populations, F is the frequency of participants with the different copies of KIR genes