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Table 2 Percentage parasitemia and chemosupression of mice treated with different doses of xylopic acid + artesunate combination for 5 days

From: Xylopic acid-amodiaquine and xylopic acid-artesunate combinations are effective in managing malaria in Plasmodium berghei-infected mice

Treatment (ED50 mg/kg)

Dose (mg/kg)

% Chem supp

Day 6

Sham

0.50 ml

–

(XA/ART)16

0.6:0.1

21.5 ± 0.6

(XA/ART)/8

1.13:0.2

24.1 ± 0.5

(XA/ART)/4

2.25:0.4

52.2 ± 0.8

(XA/ART)/2

4.5:0.8

66.8 ± 0.1

(XA/ART) 10.6

9.0:1.61

75.7 ± 1.2

AL 1.14

–

84.6 ± 1.6

  1. Data are presented as mean ± SEM, (n = 5)
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Malaria Journal

ISSN: 1475-2875

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