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Table 3 Percentage parasitemia and chemosupression of mice treated with different doses of xylopic acid + amodiaquine combination for 5 days

From: Xylopic acid-amodiaquine and xylopic acid-artesunate combinations are effective in managing malaria in Plasmodium berghei-infected mice

Treatment (ED50 mg/kg)

Dose (mg/kg)

% Chem sup

Day 6

Sham

0.50 ml

–

(XA/AQ)/16

0.6:0.2

41.2 ± 1.3

(XA/AQ)/8

1.125:0.4

43.9 ± 1.9

(XA/AQ)/4

2.25:0.8

56.4 ± 0.8

(XA/AQ)/2

4.5:1.6

68.4 ± 1.3

(XA/AQ) 12.1

9.0:3.1

79.8 ± 0.9

AL 1.14

–

88.3 ± 0.4

  1. Data are presented as mean ± SEM, (n = 5)