Xylopic acid-amodiaquine and xylopic acid-artesunate combinations are effective in managing malaria in Plasmodium berghei-infected mice

Table 4 Thirty-day survival analysis of Plasmodium berghei-infected mice after treatment with xylopic acid and amodiaquine, and xylopic acid and artesunate

Treatment (mg/kg)	Median survival (days)	Hazard ratio (log-rank)	p-value
Sham	10.5
(XA/ART)
0.7	10	0.52	0.1766
1.3	12	0.59	0.2941
2.7	16	0.35	0.0374*
5.3	16	0.35	0.0374*
10.6	19	0.23	0.0021**
(XA/AQ)
0.8	13	0.34	0.0297*
1.6	15	0.14	0.0297*
3.1	15	0.33	0.0224*
6.1	20	0.29	0.0112*
12.1	24	0.23	0.0021**
AL	27	0.21	0.0021**

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