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Table 5 Theoretical (Zadd), and experimental (Zexp) ED50 of xylopic acid and artesunate, and xylopic acid and amodiaquine co-administration in the anti-malarial assay

From: Xylopic acid-amodiaquine and xylopic acid-artesunate combinations are effective in managing malaria in Plasmodium berghei-infected mice

ED50s (XA/ART 1:1)

Anti-malarial activity

ED50s (XA/AQ 1:1)

Anti-malarial activity

Zadd (mg/kg)

5.3 ± 2.61

Zadd (mg kg−1)

6.05 ± 2.0

Zexp (mg/kg)

1.98 ± 0.25

Zexp (mg kg−1)

1.69 ± 0.42

Interaction index

0.37

Interaction index

0.28

  1. Data are presented as mean ± SEM