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Table 3 Diagnostic properties of the UsmRDT and the mRDT kits

From: Diagnostic performance of an ultrasensitive HRP2-based malaria rapid diagnostic test kit used in surveys of afebrile people living in Southern Ghana

 

UsmRDT value

95% CI

mRDT value

95% CI

 

(Lower CI–Upper CI)

Lower CI–Upper CI

Simiw

 Sensitivity

67.24 (117/174)

59.66–74.04

59.77 (104/174)

44.77–67.07

 Specificity

87.86 (152/173)

81.82–92.16

91.91 (159/173)

86.53–95.34

 PPV

84.78 (117/138)

77.45–90.12

88.13 (104/128)

80.57–93.12

 NPV

72.72 (152/209)

66.01–78.53

69.43 (159/229)

62.96–75.24

Obom

 Sensitivity

83.48 (96/115)

75.15–89.51

72.81 (83/114)

63.53–80.51

 Specificity

85.71 (150/175)

79.44–90.37

88.57 (155/175)

82.68–92.71

 PPV

79.34 (96/121)

70.83–85.95

80.58 (83/103)

71.37–87.46

 NPV

88.76 (150/169)

82.77–92.92

83.33 (155/184)

77.02–88.23

Ewim

 Sensitivity

53.84 (7/13)

26.12–79.60

53.84 (7/13)

26.12–79.60

 Specificity

100.00 (87/87)

94.73–100.00

100.00 (87/87)

94.73–100.00

 PPV

100.00 (7/7)

56.09–100.00

100.00 (7/7)

56.09–100.00

 NPV

93.55 (87/93)

85.95–97.35

93.55 (87/93)

85.95–97.35

Total

 Sensitivity

72.85 (220/302)

67.40–77.71

64.8 (197/301)

59.11–70.11

 Specificity

89.43 (389/435)

86.06–92.08

92.18 (401/435)

89.14–94.45

 PPV

82.71 (220/266)

77.50–86.94

85.28 (197/231)

79.90–89.46

 NPV

82.59 (389/471)

78.79–85.84

78.94 (401/508)

75.08–82.35

  1. NPV: negative predictive value; PPV: positive predictive value; mRDT: SD Bioline Malaria Ag P.f RDT kit; UsmRDT: ultra-sensitive Alereâ„¢ Malaria Ag P.f RDT; 95% CI: 95% confidence interval. The data represents values obtained after setting results obtained from PCR as the reference diagnostic tool