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Table 3 Diagnostic properties of the UsmRDT and the mRDT kits

From: Diagnostic performance of an ultrasensitive HRP2-based malaria rapid diagnostic test kit used in surveys of afebrile people living in Southern Ghana

  UsmRDT value 95% CI mRDT value 95% CI
  (Lower CI–Upper CI) Lower CI–Upper CI
Simiw
 Sensitivity 67.24 (117/174) 59.66–74.04 59.77 (104/174) 44.77–67.07
 Specificity 87.86 (152/173) 81.82–92.16 91.91 (159/173) 86.53–95.34
 PPV 84.78 (117/138) 77.45–90.12 88.13 (104/128) 80.57–93.12
 NPV 72.72 (152/209) 66.01–78.53 69.43 (159/229) 62.96–75.24
Obom
 Sensitivity 83.48 (96/115) 75.15–89.51 72.81 (83/114) 63.53–80.51
 Specificity 85.71 (150/175) 79.44–90.37 88.57 (155/175) 82.68–92.71
 PPV 79.34 (96/121) 70.83–85.95 80.58 (83/103) 71.37–87.46
 NPV 88.76 (150/169) 82.77–92.92 83.33 (155/184) 77.02–88.23
Ewim
 Sensitivity 53.84 (7/13) 26.12–79.60 53.84 (7/13) 26.12–79.60
 Specificity 100.00 (87/87) 94.73–100.00 100.00 (87/87) 94.73–100.00
 PPV 100.00 (7/7) 56.09–100.00 100.00 (7/7) 56.09–100.00
 NPV 93.55 (87/93) 85.95–97.35 93.55 (87/93) 85.95–97.35
Total
 Sensitivity 72.85 (220/302) 67.40–77.71 64.8 (197/301) 59.11–70.11
 Specificity 89.43 (389/435) 86.06–92.08 92.18 (401/435) 89.14–94.45
 PPV 82.71 (220/266) 77.50–86.94 85.28 (197/231) 79.90–89.46
 NPV 82.59 (389/471) 78.79–85.84 78.94 (401/508) 75.08–82.35
  1. NPV: negative predictive value; PPV: positive predictive value; mRDT: SD Bioline Malaria Ag P.f RDT kit; UsmRDT: ultra-sensitive Alere™ Malaria Ag P.f RDT; 95% CI: 95% confidence interval. The data represents values obtained after setting results obtained from PCR as the reference diagnostic tool