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Fig. 21 | Malaria Journal

Fig. 21

From: Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa

Fig. 21

Pathway 19 Human health: Potentially increased biting rate of dsxFCRISPRh transgenics could increase disease transmission in humans. Although increased biting on humans (a2) could lead to increases in vectorial capacity, overall the net effect of the population suppression gene drive could ultimately be to reduce this potential harm by reducing the density of mosquitoes (A) including transgenic ones. The components of vectorial capacity (V) that would be affected in this pathway are shown in red in the equation

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