Skip to main content
Fig. 34 | Malaria Journal

Fig. 34

From: Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa

Fig. 34

Pathway 32 Animal health: Potentially decreased mosquito defence response to pathogen in dsxFCRISPRh transgenics from altered levels of endogenous RNA, protein or microbiome could lead to increased disease in livestock. Mosquito RNA or protein in saliva, midgut or haemolymph, or contents of the microbiome, can alter defence responses to human pathogens such as Plasmodium or ONNV [112,113,114,115,116]. The components of vectorial capacity (V) that would be affected in this pathway are shown in red in the equation

Back to article page
\