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Table 2 Polymorphisms of CDS mutation in CYP2D6 gene between different vivax malaria cases

From: The association of CYP2D6 gene polymorphisms in the full-length coding region with higher recurrence rate of vivax malaria in Yunnan Province, China

SR group NR group ORc 95%CI P SNP ID in Genbank
Loci Codon changea Amino acid change No
(n = 88, %b1)
Loci Codon changea Amino acid change No. (n = 150, %b2) Upper limit Low limit
c.31 GTG > ATG V11M 1 (0.7) rs769258
c.100 CCA > TCA P34S 47 (53.4) c.100 CCA > TCA P34S 95 (63.3) 0.664 0.389 1.133 0.132d (NS) rs1065852
c.271 CTG > ATG L91M 4 (4.5) c.271 CTG > TTG L91L 2 (1.3) 3.524 0.632 19.647 0.272d (NS) rs28371703
c.281 CAC > CGC H94R 4 (4.5) rs28371704
c.294 ACC > ACG T98T 4 (4.5) c.294 ACC > ACG T98T 1 (0.7) 7.095 0.780 64.521 0.122d (NS) rs28371705
c.297 GCC > GCT A99A 1 (1.4) rs200269944
c.336 TTC > TTT F112F 42 (47.7) c.336 TTC > TTT F112F 81 (54.0) 0.778 0.459 1.318 0.350d (NS) rs1081003
c.408 GTG > GTC V136V 75 (85.2) c.408 GTG > GTC V136V 114 (76.0) 1.822 0.907 3.661 0.089d (NS) rs1058164
c.505 GGT > AGT G169S 2 (2.3) rs5030865
c.801 CCC > CCA P267P 2 (1.3) rs28371718
c.886 CGC > TGC R296C 22 (23.9) c.886 CGC > TGC R296C 20 (13.3) 2.167 1.104 4.252 0.023d (S) rs16947
c.1457 AGC > ACC S486T 75 (85.2) c.1457 AGC > ACC S486T 108 (72.0) 1.416 0.819 2.447 0.212d (NS) rs1135840