Skip to main content

Table 2 Definition of malaria-related epidemiological measures used in the model

From: Cost and cost-effectiveness of indoor residual spraying with pirimiphos-methyl in a high malaria transmission district of Mozambique with high access to standard insecticide-treated nets

Health facility-based malaria incidence

Calculated from confirmed malaria cases seeking care at public health facilities and community health workers in Mopeia, measured following an enhanced passive surveillance approach

Used in the main analysis for both cohorts

Community-based malaria incidence

Calculated from an active cohort of children under five years of age at community level

Used in the univariate sensitivity analysis for the children under five cohort

Malaria prevalence

Calculated in individuals of all ages for both study arms from the 2018 cross-sectional survey at the peak of the transmission season (April – May)

Used in the univariate sensitivity analysis for both cohorts

Severe malaria case

Malaria case requiring hospital admission. Computed from the total number of malaria infected according to the malaria severity ratio obtained from the trial

Used in the main analysis for both cohorts

Uncomplicated malaria case

Malaria case not requiring hospital admission

Malaria case fatality rate

Malaria-associated case fatality rate estimated by the Global Burden of Disease (GBD) for the most current estimate (2017). Different estimates were used for the children under five and all age cohort

Used in the main analysis for both cohorts

IRS with community-wide protective effect

IRS achieving high coverage (> 85%) so that the population target benefits from a “mass effect” on the vector population [33]

Used in the univariate sensitivity analysis for both cohorts

  1. IRS indoor residual spraying