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Table 2 IFNL4 genotype and allelic determinant for G6PD deficiency and SCT genotype; stratified by IFNL4 allele

From: IFN-λ4 genetic variants influence clinical malaria episodes in a cohort of Kenyan children

  IFNL4-dG allele (dG/dG and dG/TT genotypes combined) N = 95 (%) IFNL4-TT/TT genotype (N = 27) (%) Overall (N = 22) (%)
IFNL4 genotype
 dG/dG 40 (42) 0 (0) 40 (33)
 dG/TT 55 (58) 0 (0) 55 (45)
 TT/TT 0 (0) 27 (100%) 27 (22)
G6PD deficiency allelic determinant
 A-(G6PD deficiency) 19 (20) 4 (15) 23 (19)
 A + (G6PD wild type) 76 (80) 23 (85) 99 (81)
Sickle cell trait genotype
 Hb-A/A (wild type) 80 (84) 18 (67) 98 (80)
 Hb-A/S (sickle cell trait carriers) 15 (16 9 (33) 24 (20)
  1. Genetic distribution of study participants including IFNL4 genotype, allelic determinant for glucose-6-phosphate (G6PD) deficiency and SCT (sickle cell trait) genotype; all stratified by IFNL4 allele