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Table 2 Overall sensitivity and specificity of the nested PCR and LAMP assay

From: Validation of SYBR green I based closed‐tube loop‐mediated isothermal amplification (LAMP) assay for diagnosis of knowlesi malaria

Methods P. knowlesi Healthy donor Overall Sensitivity (%) (95% CI) Overall Specificity (%) (95% CI)
Microscopy     
 Positive 71 0   
 Negative 0 20   
Nested PCR     
 Positive 47 0 66.2 (54–77) 100 (83.2–100)
 Negative 24 20   
LAMP     
 Positive 69 0 97.1 (90.2–99.7) 100 (83.2–100)
 Negative 2 20