Table 2 Overall sensitivity and specificity of the nested PCR and LAMP assay
Methods | P. knowlesi | Healthy donor | Overall Sensitivity (%) (95% CI) | Overall Specificity (%) (95% CI) |
|---|---|---|---|---|
Microscopy | ||||
Positive | 71 | 0 | ||
Negative | 0 | 20 | ||
Nested PCR | ||||
Positive | 47 | 0 | 66.2 (54–77) | 100 (83.2–100) |
Negative | 24 | 20 | ||
LAMP | ||||
Positive | 69 | 0 | 97.1 (90.2–99.7) | 100 (83.2–100) |
Negative | 2 | 20 |