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Table 1 Prevalence and density of P. falciparum at baseline and endpoint

From: Gametocyte carriage of Plasmodium falciparum (pfs25) and Plasmodium vivax (pvs25) during mass screening and treatment in West Timor, Indonesia: a longitudinal prospective study

  Baseline Endpoint p value OR/GMR (95%CI)
Parasite prevalence
 By microscopy 22/811 (3%)a 34/740 (5%)b 0.056 1.73 (0.97–3.13)
 By PCR 49/811 (6%) 42/740 (6%) 0.829 0.94 (0.60–1.46)
 By either test 52/811 (6%) 50/740 (7%) 0.838 1.06 (0.69–1.61)
 Median parasitaemia/µL (IQR) (microscopy) 440 (80–1800) 860 (92–2690) 0.351  
 Median 18S copies/µL (IQR) (qPCR) (n baseline = 33, endpoint = 29) 59.4 (7.8–1475.0) 713.5 (7.6–899.1) 0.095  
Gametocyte prevalence
 By microscopy 11/811 (1.4%) 15/740 (2.0%) 0.328 1.50 (0.64–3.65)
 By pfs25 19/803 (2%) 23/729 (3%) 0.353 1.34 (0.69–2.63)
 By either test 19/803 (2%) 23/729 (3%) 0.353 1.34 (0.69–2.63)
Gametocyte density (per μL)
 By microscopy (median) (IQR) 80 (48–280) 460 (80–860) 0.085  
 By pfs25 (geometric mean) (95%CI) 132.5 (30.2–580.5) 210.9 (56.8–782.7) 0.625 0.6 (0.1–4.2)
  1. OR odds ratio, GMR geometric mean ratio
  2. aThree and beight subjects were not confirmed by PCR during baseline and endpoint, respectively. This is presumably due to degraded DNA and possible LM false positive given 10 of 11 (90%) showed negative microscopy during cross check