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Table 1 Demographic and clinical characteristics of 762 in-patients, Uganda

From: Quality of care for adult in-patients with malaria in a tertiary hospital in Uganda

Characteristic

Anti-malarial Use during the Current Hospitalization

Yes

No

Overall

Age, yearsa

27 (21–35)

30 (25–43)

30 (24–42)

Length of hospital stay, daysa

4 (3–5)

4 (3–6)

4 (3–6)

Patient-days of observation

454

3287

3741

Extent of anti-malarial use

Anti-malarial Use during the Current Hospitalization, n (%)

Yes

No

Total

Pre-admission anti-malarials

97 (13)

665 (87)

762

In-hospital anti-malarials

100 (13)

662 (87)

762

Pre-admission anti-malarials

38 (38)

62 (62)

100

Pre-/in-hospital co-trimoxazole

15 (15)

85 (85)

100

In-hospital antibiotics

61 (61)

39 (39)

100

In-hospital antiretrovirals

14 (14)

86 (86)

100

Pre-/in-hospital anti-malarials

159 (21)

603 (79)

762

Subgroup analyses on key variables

Anti-malarial Use, n (%)

Single factor analysis

Yes

No

Total, [% col]b

ORc

95% CId for OR

P-value

Gender

 Male

20 ( 9)

208 (91)

228 [30]

1.0

  

 Female

80 (15)

454 (85)

534 [70]

1.8

1.09–3.07

0.022

Ward

 Gynaecological (GYN)

25 (13)

166 (87)

191 [25]

1.0

  

 Infectious Diseases and Gastrointestinal Illnesses (IDGI)

57 (18)

263 (82)

320 [42]

1.4

0.87–2.39

0.161

 Haematology, Neurology and Endocrinology (HNE)

12 (10)

105 (90)

117 [15]

0.8

0.37–1.58

0.459

 Cardiovascular, Pulmonology and Nephrology (CPN)

6 ( 4)

128 (96)

134 [18]

0.3

0.12–0.78

0.013

Number of working diagnoses

 One

21 (15)

122 (85)

143 [18]

1.0

  

 Two

26 (13)

177 (87)

203 [27]

0.9

0.46–1.59

0.616

 Three

28 (15)

158 (85)

186 [24]

1.0

0.56–1.90

0.926

 Four or more

25 (11)

205 (89)

230 [30]

0.7

0.38–1.32

0.277

Length of hospital stay, days

 Less than 5-days

64 (15)

368 (85)

432 [57]

1.0

  

 Five days or more

36 (11)

294 (89)

330 [43]

0.7

0.46–1.09

0.115

HIV-serostatus

 Negative

49 (14)

291 (86)

340 [45]

1.0

  

 Positive

23 (10)

209 (90)

232 [30]

0.7

0.39–1.11

0.113

 Unknown

28 (15)

162 (85)

190 [25]

1.0

0.62–1.70

0.919

Hospitalization in past 3-months

 No

75 (14)

455 (86)

532 [70]

1.0

  

 Yes

25 (11)

205 (89)

230 [30]

0.7

0.46–1.20

0.227

Charlson's co-morbidity index score

 Zero

64 (16)

329 (84)

393 [52]

1.0

  

 One or more

36 (10)

333 (90)

369 [48]

0.6

0.36–0.86

0.008

Antiretroviral therapy use

 No

86 (14)

549 (86)

635 [83]

1.0

  

 Yes

14 (11)

113 (89)

127 [17]

0.8

0.43–1.44

0.444

Microscopy—Malaria Parasitaemia Results Available

 No

62 (62)

616 (93)

678 [89]

1.0

  

 Yes

38 (38)

46 ( 7)

84 [11]

8.2

4.81–14.0

 < 0.001

Major admission diagnosis

Malaria

      

 No

17 ( 3)

604 (97)

621 [81]

1.0

  

 Yes

83 (59)

58 (41)

141 [19]

50

28.3–91.5

 < 0.001

Immunosuppressed syndrome (ISS) or HIV/AIDSe

 No

86 (14)

524 (86)

610 [80]

1.0

  

 Yes

14 ( 9)

14 (91)

152 [20]

0.6

0.34–1.12

0.113

Tuberculosis (TB)

 No

92 (14)

548 (86)

640 [84]

1.0

  

 Yes

8 ( 7)

114 (93)

122 [16]

0.4

0.20–0.88

0.023

Sepsis-related working diagnosis

No

81 (12)

597 (88)

678 [89]

1.0

  

Yes

19 (23)

65 (77)

84 [11]

2.2

1.23–3.78

0.007

Respiratory Conditions except TB

      

 No

85 (13)

547 (87)

632 [83]

1.0

  

 Yes

15 (12)

115 (88)

130 [17]

0.8

0.47–1.51

0.557

Miscellaneous infections

 No

78 (12)

571 (88)

649 [85]

1.0

  

 Yes

22 (19)

91 (81)

113 [15]

1.8

1.05–2.98

0.032

  1. aMedian (Interquartile Range, IQR)
  2. b% Column
  3. cOR Odds Ratio
  4. dconfidence interval
  5. eNot all HIV-positive patients had the immunosuppressed syndrome, ISS