Historical trends and new surveillance of Plasmodium falciparum drug resistance markers in Angola

Malaria Journal

Table 3 Frequency of the CQ-resistant crt 76T allele in Angola since the early 2000s

Year	76T	Province	Recruitment	Notes	Ref
2004	93.9%	Uíge	Children 4–108 months in hospital emergency unit	–	[36]
2007	93.9%	Luanda	Children 1–16 years with uncomplicated malaria in hospital	Year approximate	[54]
2007	97.1%	Luanda	Adults > 18 years with uncomplicated malaria	76T primarily on SVMNT haplotype	[30]
2010	50.7%	Bengo	Baseline prevalence survey in women and children	–	[55]
2010–11	88.9%	Benguela	Random household survey of children < 15 years	Mixed infections not mentioned	[56]
2012–14	44.4%	–	Migrant workers returning to China	–	[57]
2012–15	29.9%	–	Migrant workers returning to China	–	[58]
2012–16	38.1%	–	Migrant workers returning to China	Mixed infections not mentioned	[59]
2018	70.7%	Cabinda	Adults and children in hospital	–	This study

Each allele frequency was re-calculated from published prevalence data to include mixed infections whenever possible (see Additional file 5: Table S5)

ISSN: 1475-2875