Skip to main content

Table 4 Association between clinical manifestation and allelic subfamilies

From: Allelic diversity of merozoite surface protein genes (msp1 and msp2) and clinical manifestations of Plasmodium falciparum malaria cases in Aceh, Indonesia

Clinical manifestation Allele Yes No p-value OR CI95%
n % n %
Shock K1 2 66.7 32 36.8 0.66 3.29 0.31–34.97
MAD20 0 0 42 48.3 0.29 1.07 0.99–1.15
RO33 0 0 1 1.1 1.00 1.03 1.00–1.08
K1 + MAD20 0 0 5 5.7 1.00 1.04 1.00–1.08
K1 + RO33 1 33.3 3 3.5 0.30 10.75 1.21–95.20
MAD20 + RO33 0 0 4 4.6 1.00 1.04 1.00–1.08
Convulsion K1 2 100 32 36.4 0.27 0.94 0.87–1.02
MAD20 0 0 42 47.7 0.54 1.04 0.98–1.11
RO33 0 0 1 1.1 1.00 1.02 0.99–1.06
K1 + MAD20 0 0 5 5.7 1.00 1.02 0.99–1.06
K1 + RO33 0 0 4 4.6 1.00 1.02 0.99–1.06
MAD20 + RO33 0 0 4 4.6 1.00 1.02 0.99–1.06
Conscious disturbance K1 2 50 32 37.2 1.00 1.65 0.24–11.16
MAD20 0 0 42 48.8 0,16 1.09 1.00–1.19
RO33 0 0 1 1.2 1,00 1.05 1.00–1.10
K1 + MAD20 0 0 5 5.8 1.00 1.05 1.00–1.10
K1 + RO33 1 25 3 3.5 0.42 7.17 0.94–54.51
MAD20 + RO33 1 25 3 3.5 0.42 7.17 0.94–54.51
Anaemia K1 14 42.4 20 35.1 0.64 1.21 0.71–2.09
MAD20 17 51.5 25 43.9 0.63 1.21 0.71–2.09
RO33 1 3 0 0 0.78 2.78 2.11–3.67
K1 + MAD20 1 3.1 4 7 0.75 0.53 0.09–3.13
K1 + RO33 0 0 4 7 0.31 1.62 1.37–1.92
MAD20 + RO33 0 0 4 7 0.31 1.62 1.37–1.92
Haemoglobinuria K1 9 50 25 34.7 0.36 1.65 0.73–3.74
MAD20 6 33.3 36 50 0.32 0.57 0.24–1.39
RO33 0 0 1 1.3 1.00 1.25 1.13–1.39
K1 + MAD20 1 5.6 4 5.6 1.00 1.00 0.16–6.07
K1 + RO33 2 11.1 2 2.8 0.37 2.69 0.92–7.87
MAD20 + RO33 0 0 4 5.6 0.70 1.26 1.13–1.41
Splenomegaly K1 29 36.7 5 45.4 0.82 0.96 0.81–1.13
MAD20 38 48.1 4 36.4 0.68 1.06 0.91–1.23
RO33 1 1.3 0 0 1.00 1.14 1.06–1.23
K1 + MAD20 5 6.3 0 0 0.88 1.15 1.06–1.25
K1 + RO33 3 3.8 1 9.1 0.99 0.85 0.48–1.50
MAD20 + RO33 3 3.8 1 9.1 0.99 0.85 0.48–1.50
MAD20 26 45.6 16 48.5 0.90 1.06 0.76–1.49
RO33 1 1.8 0 0 1.00 1.68 1.41–1.99
K1 + MAD20 1 7 1 3 0.16 0.32 0.06–1.87
K1 + RO33 4 7 0 0 0.25 1.72 1.44–2.06
MAD20 + RO33 2 3.5 2 6.1 1.00 0.83 0.31–2.24
Dyspnea K1 26 38.3 8 36.4 1.00 1.00 0.79–1.26
MAD20 33 48.5 9 40.9 0.88 1.05 0.83–1.31
RO33 1 1.5 0 0 1.00 1.31 1.17–1.47
K1 + MAD20 2 2.9 3 13.7 0.15 0.51 0.17–1.49
K1 + RO33 3 4.4 1 4.5 0.86 0.81 0.05–47.66
MAD20 + RO33 3 4.4 1 4.5 0.86 0.81 0.05–47.66
Abnormality in the value of kidney function K1 32 37.2 2 50
MAD20 40 46.5 2 50
RO33 1 1.3 0 0
K1 + MAD20 5 5.8 0 0
K1 + RO33 4 4.6 0 0
MAD20 + RO33 4 4.6 0 0
Fever (≥ 39.0 °C) K1 23 44.2 11 28.9 0.22 1.84 0.6–5.66
MAD20 17 32.7 25 65.8
RO33 1 1.9 0 0 0.22 1.84 0.6–5.66
K1 + MAD20 3 5.8 2 5.3
K1 + RO33 4 7.7 0 0
MAD20 + RO33 4 7.7 0 0 0.77 1.32 0.13–17.73