Clinical manifestation | Allele | Yes | No | p-value | OR | CI95% | ||
---|---|---|---|---|---|---|---|---|
n | % | n | % | |||||
Shock | 3D7 | 1 | 33.3 | 36 | 41.4 | 1.00 | 0.72 | 0.07–7.61 |
FC27 | 2 | 66.7 | 32 | 36.8 | 0.66 | 3.29 | 0.31–34.97 | |
FC27 + 3D7 | 0 | 0 | 19 | 21.8 | 0.85 | 1.04 | 0.99–1.10 | |
Convulsion | 3D7 | 1 | 50 | 36 | 40.9 | 1.00 | 1.43 | 0.09–22.18 |
FC27 | 1 | 50 | 33 | 37.5 | 1.00 | 1.65 | 0.11–25.48 | |
FC27 + 3D7 | 0 | 0 | 19 | 21.6 | 1.00 | 1.03 | 0.99–1.07 | |
Conscious disturbance | 3D7 | 2 | 50 | 35 | 40.7 | 1.00 | 1.43 | 0.21–9.72 |
FC27 | 1 | 25 | 33 | 38.4 | 0.99 | 0.55 | 0.06–5.07 | |
FC27 + 3D7 | 1 | 25 | 18 | 20.9 | 1.00 | 1.25 | 0.14–11.31 | |
Anaemia | 3D7 | 15 | 45.5 | 22 | 38.6 | 0.68 | 1.19 | 0.69–2.05 |
FC27 | 10 | 30.3 | 24 | 41.2 | 0.38 | 0.72 | 0.39–1.32 | |
FC27 + 3D7 | 8 | 24.2 | 11 | 19.3 | 0.78 | 1.20 | 0.65–2.21 | |
Haemoglobinuria | 3D7 | 5 | 27.8 | 32 | 44.5 | 0.31 | 0.55 | 0.21–1.41 |
FC27 | 11 | 61.1 | 23 | 31.9 | 0.04 | 2.59 | 1.11–6.03 | |
FC27 + 3D7 | 2 | 11.1 | 17 | 23.6 | 0.40 | 0.47 | 0.12–1.86 | |
Splenomegaly | 3D7 | 32 | 40.5 | 5 | 45.4 | 1.00 | 0.98 | 0.83–1.14 |
FC27 | 31 | 39.2 | 3 | 27.3 | 0.66 | 1.06 | 0.92–1.24 | |
FC27 + 3D7 | 16 | 20.3 | 3 | 27.3 | 0.89 | 0.95 | 0.77–1.17 | |
Abnormality in the value of liver function | 3D7 | 27 | 47.4 | 10 | 30.3 | 0.17 | 1.29 | 0.95–1.75 |
FC27 | 25 | 43.8 | 9 | 27.3 | 0.18 | 1.29 | 0.95–1.74 | |
FC27 + 3D7 | 5 | 8.8 | 14 | 42.4 | 0.00 | 1.36 | 0.17–0.77 | |
Dyspnea | 3D7 | 27 | 39.7 | 10 | 45.4 | 0.82 | 0.94 | 0.71–1.20 |
FC27 | 28 | 41.2 | 6 | 27.3 | 0.36 | 1.15 | 0.92–1.45 | |
FC27 + 3D7 | 13 | 19.1 | 6 | 27.3 | 0.61 | 0.88 | 0.63–1.23 | |
Abnormality in the value of kidney function | 3D7 | 35 | 40.7 | 2 | 50 | 1.00 | 0.98 | 0.90–1.08 |
FC27 | 33 | 38.4 | 1 | 25 | 0.99 | 1.03 | 0.94–1.12 | |
FC27 + 3D7 | 18 | 20.9 | 1 | 25 | 1.00 | 0.99 | 0.88–1.11 | |
Fever (≥ 39.0 °C) | 3D7 | 18 | 34.6 | 19 | 50 | 0.21 | 0.76 | 0.51–1.12 |
FC27 | 24 | 46.2 | 10 | 26.3 | 0.09 | 1.41 | 1.00–1.98 | |
FC27 + 3D7 | 10 | 19.2 | 9 | 23.7 | 0.80 | 0.89 | 0.56–1.42 |