Predictors | Early treatment failure* | Late treatment failure* | ||||||
---|---|---|---|---|---|---|---|---|
Yes (n = 19) | No (n = 246) | P value | OR (95% CI) | Yes (n = 51) | No (n = 214) | P value | OR (95% CI) | |
Male | 84.2 (16) | 83.3 (205) | 0.5a | 90.2 (46) | 81.8 (175) | 0.1c | ||
Living in or travelling to malaria endemic areas 14 days prior to the onset of disease | 0.112b | 0.4b | ||||||
Living in endemic area | 36.8 (7) | 45.5 (112) | 41.2 (21) | 45.8 (98) | ||||
Travel to endemic area | 26.3 (5) | 37.4 (92) | 35.3 (18) | 36.9 (79) | ||||
Not living and not traveling to endemic area | 36.8 (7) | 17.1 (42) | 23.5 (12) | 17.3 (37) | ||||
Acquiring malaria before 2017 | 63.2 (12) | 43.1 (106) | 0.09c | 47.1 (24) | 43.9 (94) | 0.7c | ||
Number of days of illness at the time of admission > 7 days | 10.5 (2) | 26.5 (65) | 0.17a | 29.4 (15) | 24.3 (52) | 0.5c | ||
Hyperparasitaemia | 0 | 0.4 (1) | 1a | 0 | 0.5 (1) | 1a | ||
Severe malaria | 63.2 (12) | 18.7 (46) | < 0.001a | 7.5 (2.8–20.0) | 15.7 (8) | 29.9 (50) | 0.044c | 0.44 (0.19–0.99) |
Age (years) | 41.7 ± 12.5 | 34.8 ± 13.0 | 0.027d | 32.1 ± 12.3 | 36.1 ± 13.2 | 0.054d | ||
Patients with parasitaemia 72 h of treatment | 25 (12) | 13.5 (28) | 0.047c | 2.14 (0.99–4.61) | ||||
Patients with fever 3 days of treatment | 14.6 (6) | 15.8 (29) | 0.9c |