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Table 6 Unadjusted predictors tested for early and late treatment failures

From: Predictors of treatment failures of plasmodium falciparum malaria in Vietnam: a 4-year single‐centre retrospective study

Predictors Early treatment failure* Late treatment failure*
Yes
(n = 19)
No
(n = 246)
P value OR (95% CI) Yes
(n = 51)
No
(n = 214)
P value OR (95% CI)
Male 84.2 (16) 83.3 (205) 0.5a   90.2 (46) 81.8 (175) 0.1c  
Living in or travelling to malaria endemic areas 14 days prior to the onset of disease    0.112b     0.4b  
 Living in endemic area 36.8 (7) 45.5 (112)    41.2 (21) 45.8 (98)   
 Travel to endemic area 26.3 (5) 37.4 (92)    35.3 (18) 36.9 (79)   
 Not living and not traveling to endemic area 36.8 (7) 17.1 (42)    23.5 (12) 17.3 (37)   
Acquiring malaria before 2017 63.2 (12) 43.1 (106) 0.09c   47.1 (24) 43.9 (94) 0.7c  
Number of days of illness at the time of admission > 7 days 10.5 (2) 26.5 (65) 0.17a   29.4 (15) 24.3 (52) 0.5c  
Hyperparasitaemia 0 0.4 (1) 1a   0 0.5 (1) 1a  
Severe malaria 63.2 (12) 18.7 (46) < 0.001a 7.5 (2.8–20.0) 15.7 (8) 29.9 (50) 0.044c 0.44 (0.19–0.99)
Age (years) 41.7 ± 12.5 34.8 ± 13.0 0.027d   32.1 ± 12.3 36.1 ± 13.2 0.054d  
Patients with parasitaemia 72 h of treatment      25 (12) 13.5 (28) 0.047c 2.14 (0.99–4.61)
Patients with fever 3 days of treatment      14.6 (6) 15.8 (29) 0.9c  
  1. * %(N) for categorical variables and Mean ± SD for continuous variables
  2. a Fisher’s Exact test
  3. b Chi-square for trend test
  4. c Chi-square test
  5. d Student’s t test