Skip to main content

Table 6 Observed ranges of enzyme activity and G6PD genotypes identified by HRM assay

From: Glucose-6-phosphate dehydrogenase mutations in malaria endemic area of Thailand by multiplexed high‐resolution melting curve analysis

Gender Variant N G6PD activity (U/gHb) Nucleotide change Amino acid change WHO Classification
Male Mahidol 72 0.10-10.73 G487A Gly163Ser III
(n = 368) Chinese-5
Viangchan
1
1
2.10
0.89
C1024T
G871A
Leu342Phe
Val291Met
II
II
  Non-variant 294 7.16–18.05 - - Normal
Female Mahidol 115 0.10-17.72 G487A Gly163Ser III
(n = 357) Canton 4 6.50-10.48 G1376T Arg249Leu II
  Viangchan 2 6.07–6.25 G871A Val291Met II
  Mahidol + Canton 1 4.12 G487A + G1376T Gly163Ser + Arg249Leu II/III
  Chinese-4 + Viangchan 1 0.69 G392T + G871A Gly131Val + Val291Met II
  Non-variant 234 4.96–18.67 - - Normal