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Table 2 Novel polymorphisms of pfmdr1 and pfcrt in Plasmodium falciparum isolates

From: Molecular surveillance of anti-malarial resistance pfcrt, pfmdr1, and pfk13 polymorphisms in African Plasmodium falciparum imported parasites to Wuhan, China

Gene Referencea Mutationb Number of isolates
Codon position AAc Codon AAc Codon Base position PCR positive Sequencing Mutation Prevalence (%, 95% CI)
pfmdr1 87 L tta L ttG 261 106 106 1 0.94(− 0.009 to 0.028)
  102 G ggt G ggC 306    2 1.89(− 0.007 to 0.045)
  102 G ggt G ggC/T 306    1 0.94(− 0.009 to 0.028)
  199 T act S Tct 595    1 0.94(− 0.009 to 0.028)
pfcrt 136 Y tat N Aat 332 90 90 2 2.22(− 0.009 to 0.053)
  140 Q caa K cCa 344    1 1.11(− 0.011 to 0.033)
  140 Q caa Q/K cA/Ca 344    1 1.11(− 0.011 to 0.033)
  1. aReference site is in bold type with lowercase
  2. bMutation site is in bold type with capital letter
  3. cAA amino acid residue