Fig. 11From: A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malariaIsobolograms for various levels of PCR-adjusted ACPR at Day 28 in African patients, regardless of age (baseline parasitaemia = 30,000/μL). The figure shows the isobolograms for African patients for various probabilities of achieving ACPR at Day 28 with a baseline parasitaemia of 30,000 parasites/μL, which was the median baseline parasitaemia observed in African children ≤ 5 yearsBack to article page