|
Using blood samples
|
Using recombinant plasmid by each target
|
|---|
|
PvCOX1-LAMP LOD 2.4 parasites/μL 95%CI 1.8–4.8
|
PvCOX1-LAMP LOD 23.9 copies/μL 95%CI 16.1–65.8
|
|---|
|
Parasites/μLa:
|
Positive/n° replicates
|
Plasmid (Copies/μL):
|
Positive/n° replicates
|
|---|
|
214.1
|
15/15
|
1684.0
|
15/15
|
|
21.4
|
15/15
|
168.4
|
15/15
|
|
2.1
|
13/15
|
16.8
|
13/15
|
|
1.1
|
9/15
|
8.5
|
7/15
|
|
0.5
|
0/15
|
3.4
|
1/15
|
|
Pvr364-LAMP LOD 3.7 parasites/μL 95%CI 2.8–7.5
|
Pvr364-LAMP LOD 27.3 copies/μL 95%CI 19.1–133.6
|
|---|
|
3D7 culture (Parasites/μL):
|
Positive/n° replicates
|
Plasmid (Copies/μL):
|
Positive/n° replicates
|
|---|
|
314.2
|
15/15
|
1865.5
|
15/15
|
|
31.4
|
15/15
|
186.6
|
15/15
|
|
3.1
|
13/15
|
18.7
|
12/15
|
|
1.6
|
6/15
|
9.3
|
4/15
|
|
0.8
|
0/15
|
1.9
|
0/15
|
|
Pvr47-LAMP LOD 3 parasites/μL 95%CI: 2.1–6.8
|
Pvr47-LAMP LOD 15.6 copies/μL 95%CI: 11.9–30.5
|
|---|
|
Parasites/μLa:
|
Positive/n° replicates
|
Plasmid (Copies/μL):
|
Positive/n° replicates
|
|---|
|
214.1
|
15/15
|
1631.6
|
15/15
|
|
21.4
|
15/15
|
163.2
|
15/15
|
|
2.1
|
12/15
|
16.3
|
14/15
|
|
1.1
|
5/15
|
8.2
|
9/15
|
|
0.5
|
0/15
|
3.3
|
0/15
|
|
PfEMP1-LAMP LOD 3.3 parasites/μL 95%CI: 2.4–6.7
|
Pvr47-LAMP LOD 28.9 copies/μL 95%CI: 21.2–86.7
|
|---|
|
3D7 culture (Parasites/μL):
|
Positive/n° replicates
|
Plasmid (Copies/μL):
|
Positive/n° replicates
|
|---|
|
314.2
|
15/15
|
2076.0
|
15/15
|
|
31.4
|
15/15
|
207.6
|
15/15
|
|
3.1
|
14/15
|
20.8
|
12/15
|
|
1.6
|
8/15
|
10.4
|
3/15
|
|
0.8
|
1/15
|
2.1
|
0/15
|
- aPool of blood samples from infected patients quantified in parasite/µL by real-time PCR
