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Table 1 Allele frequencies of non-synonymous variants in Cyp6m2 coding region

From: Genetic variation at the Cyp6m2 putative insecticide resistance locus in Anopheles gambiae and Anopheles coluzzii

Variants Population allele frequency (%)
Positiona   Agb All AOcolc GHcol BFcol CIcol GNcol GW GM CMgam GHgam BFgam GNgam GAgam UGgam GQgam FRgam KE
6928945 G > A A13T 2.8 39.7 0 0.7 0 0 0 0 0 0 0 0 0 0 0 0 0
6929047 G > C G47R 0.6 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
6929050 T > A S48T 2.8 9 0.9 4 2.1 0 3.3 2.3 3.2 4.2 2.7 2.5 0 2.2 0 0 0
6929102 A > C D65A 6.0 0 0 0 0 0 0.5 0 1.9 4.2 2.7 3.8 42.8 2.7 0 0 52.1
6929375 A > T K156I 0.4 0 0 0 0 0 0 0 0 0 0 0 1.4 0 44.4 0 0
6929506 A > G N200D 0.4 0 0 0 0 0 0 0 0 0 0 0 1.4 0 44.4 0 0
6929770 T > A S288T 1.1 0 5.5 0.7 0.7 0 0 0 0.8 4.2 2.7 1.3 0.7 1.3 0 0 0
6929881 G > A E325K 1.2 0 7.3 3.3 2.1 0 3.8 2.3 0 0 0.5 0 0 0 0 0 0
6929890 G > C E328Q 2.9 0.6 13.6 7.3 7 12.5 9.9 6.2 0.3 0 0 0 0 0 0 0 0
6929948 A > T Y347F 2.4 0 0 0 0 0 0 0 0.2 0 0 0 0 1.8 0 0 52.1
6929983 A > G I359V 16.0 0 4.5 0 7 37.5 16.5 20 19.4 25 17.4 16.3 48.6 19.6 0 0 0
6930206 C > T P407L 0.7 0 2.7 0.7 7 0 0 0 0.2 0 0 0 0 0 0 0 0
6930242 A > T E419V 0.4 5.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
6930269 A > G K428R 2.0 0 0 0.7 0 0 0.5 0.8 3.5 0 2.7 2.5 0.7 6.3 0 0 0
6930388 G > T A468S 2.6 0 0 0 0 0 0 0 0.3 0 0 0 42 0 0 0 0
  1. aPosition relative to the AgamP4 reference sequence, chromosome 3R
  2. bCodon numbering according to Anopheles gambiae AGAP008212-RA transcript in geneset AgamP4.12
  3. cAOcol, Angola An. coluzzii; GHcol, Ghana An. coluzzii; BFcol, Burkina Faso coluzzii; CIcol, Côte d'Ivoire An. coluzzii; GNcol, Guinea An. coluzzii; GW, Guinea Bissau; GM,The Gambia; CMgam, Cameroon; GHgam, Ghana An. gambiae; BFgam, Burkina Faso An. gambiae; GNgam, Guinea An. gambiae; GAgam, Gabon An. gambiae; UGgam, Uganda An. gambiae; GQgam, Equatorial Guinea An. gambiae; FRgam, Mayotte An. gambiae; KE, Kenya