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Table 2 The prevalence of parasite infection and period prevalence of clinical cases for all study villages in 2018 (n = 50)

From: Reactive, self-administered malaria treatment against asymptomatic malaria infection: results of a cluster randomized controlled trial in The Gambia

Outcome

Intervention

Control

Odds ratioa (95% confidence interval)

Infection prevalence

 All clustersb

0.8% (16/1924)

1.1% (20/1814)

0.71 (0.27, 1.84) p = 0.48

 North bank

0.3% (4/1246)

0.1% (1/1134)

3.58 (0.4, 32.1) p = 0.255

South banka

1.8% (12/665)

2.8% (19/669)

0.61 (0.29, 1.26) p = 0.182

By age

 Under 5 years

0.4% (1/237)

3.5 (7/199)

0.11 (0.01, 0.94), p = 0.043

 5–14 years

0.5% (4/783)

0.7% (5/769)

0.84 (0.22, 3.17), p = 0.8

15–30 years

1.9% (6/323)

0.7% (2/279)

2.76 (0.55, 13.9), p = 0.219

Above 30 years

0.9% (5/567)

1.1% (6/555)

0.88 (0.26, 2.91), p = 0.83

Period prevalence of clinical malaria

 All clusters

0.8% (71/8645)

0.8% (85/10330)

1.04 (0.57, 1.91) p = 0.893

 North bank

0.2% (6/3752)

0.2% (13/6064)

0.77 (0.23, 2.54) p = 0.664

 South bank

1.3% (65/4893)

1.7% (72/4266)

0.81 (0.34, 1.92) p = 0.613

  1. aRandom effects logistic regression models are not valid with a small number of clusters per arm so a t test on cluster level summaries was used; in these cases, a risk ratio is presented instead of an odds ratio
  2. bAdjusted for age