Reactive, self-administered malaria treatment against asymptomatic malaria infection: results of a cluster randomized controlled trial in The Gambia

Table 3 The prevalence of parasite infection and period prevalence of clinical cases for all study villages in 2017 (n = 34)

Outcome	Intervention	Control	Odds ratio (95% confidence interval)
Infection prevalence^a	1.8% (23/1259)	2.4% (39/1638)	0.54 (0.21, 1.37), p = 0.193
By age
Under 5 years	1.1% (2/191)	3.7% (10/2720)	024 (0.05, 1.31), p = 0.101
5–14 years	1.7% (9/538)	1.6% (11/698)	0.91 (0.29, 2.81), p = 0.865
15–30 years	3.0% (6/201)	3.6% (9/252)	0.64 (0.18, 2.31), p = 0.498
Above 30 years	1.8% (6/333)	2.1% (0/425)	0.81 (0.23, 2.8), p = 0.734
Period prevalence of clinical malaria	0.3% (12/3752)	0.3% (18/6064)	0.95 (0.30–2.97), p = 0.930

^aRandom effects logistic regression models are not valid with a small number of clusters per arm so a t test on cluster level summaries was used; in these cases, a risk ratio is presented instead of an odds ratio

ISSN: 1475-2875