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Table 4 Multiplicity of infection (MOI) per msp-1 or msp-2 and combined msp-1/msp-2 genotype, by study site, age group and parasite density group

From: Genetic diversity of Plasmodium falciparum populations in three malaria transmission settings in Madagascar

Variable

No. isolates

No. genotypes

MOI (SD)

msp-1

msp-2

msp-1

msp-2

msp-

1

P-value*

msp-

2

P-value*

msp-1/-2

P-value*

Overall

221

164

1–4

1–3

1.64 (0.77)

–

1.34 (0.57)

–

2.28 (1.54)

–

By site

      

 Anjoma Ramartina (Fringes)

67

55

1–3

1–2

1.51 (0.68)

0.001

1.27 (0.45)

NS

2.02 (1.18)

0.04

 Antanimbary (Tropical)

80

54

1–3

1–3

1.50 (0.63)

1.50 (0.69)

2.25 (1.51)

 Tsaratanana (Equatorial)

74

55

1–4

1–3

1.92 (0.90)

1.25 (0.52)

2.52 (1.81)

By age group

  

  < 5 years

58

41

1–4

1–3

1.74 (0.81)

NS

1.27 (0.50)

NS

2.10 (1.08)

NS

 5–15 years

108

86

1–4

1–3

1.68 (0.80)

1.34 (0.58)

2.35 (1.75)

  > 15 years

55

37

1–3

1–3

1.47 (0.63)

1.43 (0.60)

2.34 (1.56)

By parasite density group

      

  < 5000

48

39

1–3

1–2

1.50 (0.65)

NS

1.23 (0.43)

NS

1.90 (1.07)

NS

 5000–50,000

115

84

1–3

1–3

1.63 (0.80)

1.39 (0.64)

2.4 (1.78)

  > 50,000

57

39

1–4

1–3

1.77 (0.80)

1.33 (0.53)

2.33 (1.37)

  1. Significant P-values are shown in bold typeface
  2. NS not significant
  3. * ANOVA test