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Fig. 3 | Malaria Journal

Fig. 3

From: Inter-study and time-dependent variability of metabolite abundance in cultured red blood cells

Fig. 3

Rates of change in metabolite abundances (Δm/Δt) of red blood cells during the five studies. A Counts of metabolites within the range of Δm/Δt shown on the abscissa between 8 and 40 h of each experiment. B Average rate of change at the indicated time points of each experiment, where N denotes the total number of metabolites. C Hierarchical clustering of Δm/Δt across the five studies, highlighting the cluster (annotated with the number 1) with noticeably different Δm/Δt values. Note that we have computed Δm/Δt at 8, 16, 24, 32, and 40 h of the experiment (see Methods). + Fos, fosmidomycin-added RPMI medium; -Hxn, hypoxanthine-deprived RPMI medium; + Mev, mevalonate-added RPMI medium; Pure 1, pure RPMI medium; Pure 2, pure RPMI medium; RPMI, Roswell Park Memorial Institute

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