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Table 2 Meta-analysis of diagnostic performance Alere™ Ultra-sensitive Malaria Ag P. falciparum RDT according to the reference test

From: Assessing field performance of ultrasensitive rapid diagnostic tests for malaria: a systematic review and meta-analysis

N data sets

Pooled sensitivity, % [95% CI]

Heterogeneity for sensitivity (I2, %)

Pooled specificity, % [95% CI]

Heterogeneity for

specificity (I2, %)

uRDT

cRDT

uRDT

cRDT

uRDT

cRDT

uRDT

cRDT

According to reference test

 PCR

9

60.4 [50.8; 69.2]

49.4 [38.2; 60.6]

89.4

92.6

97.5 [94.1; 98.9]

98.2 [95.5; 99.3]

97.6

97.1

 Ultra-sensitive PCR

4

60.3 [42.2; 75.9]

44.1 [18.8; 72.8]

93.6

97.1

99.5 [98.9; 99.8]

99.8 [99.7; 99.9]

71.9

0.0

  1. PCR Polymerase chain reaction, RDT Malaria rapid diagnostic test, CI Confidence interval