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Table 3 Median concentration (pg/ml) values for each cytokine and growth factor in plasma of P. vivax-infected and uninfected groups

From: Humoral and cellular immune response to Plasmodium vivax VIR recombinant and synthetic antigens in individuals naturally exposed to P. vivax in the Republic of Korea

  IL-2 IL-6 IL-10 IL-12 IFN- γ TNF IP-10 G-CSF
VIR25
 P. vivax 10 27 34 42 14 62 10 98
 Healthy control 13 19 31 46 11 56 12 102
 P values 0.225 0.092 0.103 0.312 0.098 0.236 0.168 0.263
VIR-C2
 P. vivax 89** 41* 102* 74* 13 112* 12 195*
 Healthy control 11 20 33 42 12 64 9 112
 P values < 0.001 0.029 0.018 0.035 0.156 0.031 0.264 0.039
PvLP1
 P. vivax 7 29 52 40 11 72 13 124
 Healthy control 10 12 39 41 12 69 10 96
 P values 0.265 0.314 0.247 0.184 0.206 0.105 0.241 0.198
PvLP2
 P. vivax 32* 72* 132** 61 13 103* 13 159*
 Healthy control 12 19 49 49 11 64 15 95
 P values 0.045 0.013  < 0.001 0.235 0.153 0.031 0.128 0.015
PvMSP1-19
 P. vivax 125** 95** 89** 58 15 120* 49 201*
 Healthy control 16 14 39 46 13 62 45 106
 P values < 0.001 < 0.001 < 0.001 0.391 0.153 0.013 0.364 0.041
GST
 P. vivax 10 25 38 51 14 67 10 116
 Healthy control 12 16 31 41 12 62 11 102
 P values 0.125 0.312 0.186 0.216 0.234 0.163 0.113 0.265
Medium
 P. vivax 10 39 35 50 13 70 10 121
 Healthy control 16 15 32 45 15 68 9 110
 P values 0.315 0.132 0.327 0.192 0.264 0.162 0.298 0.225
  1. n = 25 for P. vivax-infected groups; n = 30 for healthy control
  2. *P < 0.05 for P. vivax-infected patients versus control individuals
  3. **P < 0.001 for P. vivax-infected patients versus control individuals