Fig. 2

Estimated Day 7 concentrations of artefenomel and ferroquine measured in dry blood spots in African children ≤ 5y in relation to vomiting and PCR-adjusted ACPR at Day 28 in the prematurely discontinued extended phase 2 B studies [14]. The four quadrants were defined according to the median exposures. All patients with drug concentrations outside the yellow shaded area were “cured”