Table 1 NF10 haplotypes studied in competitive growth experiments
Haplotype | PfMDR1 sequence | Drug sensitivity (IC50, nM) | |||
|---|---|---|---|---|---|
86 | 184 | Chloroquine | Lumefantrine | Piperaquine | |
NY | Wild type | Wild type | 185 | 3.2 | 28.9 |
NF | Wild type | Mutant | 205 | 3.2 | 35.1 |
YY | Mutant | Wild type | 331 | 0.9 | 35.4 |
YF | Mutant | Mutant | 328 | 0.9 | 40.2 |