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Table 1 NF10 haplotypes studied in competitive growth experiments

From: Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum

Haplotype PfMDR1 sequence Drug sensitivity (IC50, nM)
86 184 Chloroquine Lumefantrine Piperaquine
NY Wild type Wild type 185 3.2 28.9
NF Wild type Mutant 205 3.2 35.1
YY Mutant Wild type 331 0.9 35.4
YF Mutant Mutant 328 0.9 40.2
  1. The haplotypes shown indicate the N86Y and Y184F sequences. Drug sensitivities are as reported previously [14]