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Fig. 1 | Malaria Journal

Fig. 1

From: Concomitant experimental coinfection by Plasmodium berghei NK65-NY and Ascaris suum downregulates the Ascaris-specific immune response and potentiates Ascaris-associated lung pathology

Fig. 1

Clinical and parasitological aspects of P. berghei and A. suum coinfection. A Experimental design. B Variation of body weight was expressed as a percentage from the initial weight of mice. The hatched area represents the times when statistical analysis was carried out between all groups. C Survival rate. D Larvae parasitic load in the pulmonary parenchyma and BAL on 7th day postinfection (dpi) (n = 6 per group). E Parasitaemia levels. Circles—noninfected group (n = 6), Square—P. berghei NK65-NY mono-infected group (n = 15), Triangle—A. suum mono-infected group (n = 15), Inverted triangle—coinfected group (n = 15). Survival curves were compared using the Gehan–Breslow–Wilcoxon test. Larvae burdens were compared using the Mann–Whitney test. Two-way ANOVA test followed by multiple comparisons test was used to evaluate variations in body weight and parasitaemia. The results are shown as the mean ± SEM and significant differences (p ≤ 0.05) among the groups are represented by (a) NI group, (b) Pb group and (c) As group or *p < 0.05, **p < 0.01 and ****p < 0.0001

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Malaria Journal

ISSN: 1475-2875

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