Fig. 1

Co-culture of B-cells and P. falciparum (FCR3S1.2) followed by microscopy. a Acridine orange stain in light microscopy was used for daily monitoring. B-cells are seen as large fluorescent cells. P. falciparum-infected RBCs can be seen both in direct contact with a B-cell in the centre of the picture, and as separate cells. b Confocal microscopy. Numerous parasites can be seen inside RBCs. c Confocal microscopy showing a B-cell binding to a P. falciparum-infected RBC