Fig. 5

The development of ECM in PMCA4^−/− mice during P. berghei ANKA infection. PMCA-4^−/− and WT littermate mice were infected (i.v.) with 10⁴ P. berghei ANKA pRBCs. A, B The course of infection as measured by (A) peripheral parasitaemia and B survival. C Representative pictures showing level of Evans blue penetration into brain on day 6 of infection (Evans blue injected (i.v.) 1 h prior to removal of brain). A The results are from one of three independent experiments with n = 3–5 per group, per experiment. B The data includes all mice used in the project (n = 34 per group, * P < 0.05)