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Fig. 6 | Malaria Journal

Fig. 6

From: The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria

Fig. 6

The effect of PMCA4 ablation on splenic immune responses during P. berghei ANKA infection. PMCA4−/− and WT littermate mice were infected (i.v.) with 104 P. berghei ANKA pRBCs. A, B The numbers of antigen-experienced (Ag-exp: CD11a+CD49d+) A CD4+ T cells and B CD8+ T cells in the spleen on day 6 of infection. C, D Representative histograms and percentages of splenic E Ag-exp CD4+ T cells and F Ag-exp CD8+ T cells expressing Granzyme B on day 6 of infection. (Data are from one of two independent experiments with n = 4–5 per group, per experiment)

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