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Fig. 7 | Malaria Journal

Fig. 7

From: The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria

Fig. 7

Analysis of cerebral T-cells during P. berghei infection. PMCA4−/− and WT littermate mice were infected (i.v.) with 104 P. berghei pRBCs. A, B The numbers of A Ag-exp CD4+ T cells and B Ag-exp CD8+ T cells in the brain on day 6 of infection. C, D Representative histograms and percentages of intracerebral E Ag-exp CD4+ T cells and F Ag-exp CD8+ T cells expressing Granzyme B on day 6 of infection. G The numbers of inflammatory (Ly6c+) monocytes in the brain on day 6 of infection. H and I Representative histograms and percentages of CD31+CD45 endothelial cells expressing ICAM-1 on day 6 of infection. The results are from one of two independent experiments with n = 4–5 per group, per experiment (* p < 0.05)

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