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Table 2 Limited cross-study overlap of differentially expressed genes

From: Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers

    N shared genes N expected p
Response IMRAS UP BSPZV1 UP 377 323 2.02 × 10–4
Response IMRAS DOWN BSPZV1 DOWN 244 257 0.84
Protection IMRAS UP BSPZV1 UP 14 3 7.24 × 10–7
Protection IMRAS DOWN BSPZV1 DOWN 3 2 0.32
  1. Hypergeometric test p-values and overlap sizes for the up- and down-regulated genes identified by mixed modelling