Table 3 Blood transcriptional modules enriched in overlapping differentially expressed genes
N genes | N BTM | N shared | N expected | p value | FDR | Blood transcriptional module (BTM) name | Protection associated |
|---|---|---|---|---|---|---|---|
377 | 82 | 26 | 2 | 4.58E−21 | 3.01E−18 | DC.M3.1_Erythrocytes | |
377 | 145 | 32 | 4 | 2.55E−20 | 8.35E−18 | LI.M4.1_cell cycle (I) | * |
377 | 335 | 44 | 9 | 3.53E−18 | 7.72E−16 | LI.M4.0_cell cycle and transcription | * |
377 | 49 | 17 | 1 | 6.00E−15 | 9.84E−13 | DC.M3.3_Cell Cycle | * |
377 | 77 | 20 | 2 | 1.31E−14 | 1.71E−12 | DC.M4.4_Undetermined | |
377 | 34 | 14 | 1 | 9.42E−14 | 1.03E−11 | LI.M4.2_PLK1 signaling events | * |
377 | 200 | 29 | 6 | 1.89E−13 | 1.77E−11 | HALLMARK_E2F_TARGETS | * |
377 | 200 | 27 | 6 | 7.41E−12 | 6.08E−10 | HALLMARK_HEME_METABOLISM | |
377 | 71 | 16 | 2 | 6.30E−11 | 4.59E−09 | DC.M2.3_Erythrocytes | |
377 | 35 | 11 | 1 | 1.36E−09 | 8.91E−08 | LI.M4.5_mitotic cell cycle in stimulated CD4 T cells | |
377 | 200 | 23 | 6 | 6.65E−09 | 3.97E−07 | HALLMARK_G2M_CHECKPOINT | |
377 | 51 | 10 | 1 | 1.03E−06 | 5.61E−05 | LI.M103_cell cycle (III) | |
377 | 32 | 8 | 1 | 1.79E−06 | 9.05E−05 | LI.M6_mitotic cell division | |
377 | 47 | 9 | 1 | 4.42E−06 | 2.07E−04 | LI.M49_transcription regulation in cell development | |
377 | 12 | 5 | 0 | 1.03E−05 | 4.53E−04 | LI.M4.12_C-MYC transcriptional network | |
377 | 20 | 6 | 1 | 1.16E−05 | 4.77E−04 | DC.M6.11_Cell Cycle | |
377 | 21 | 6 | 1 | 1.59E−05 | 6.13E−04 | LI.M4.7_mitotic cell cycle | |
377 | 14 | 5 | 0 | 2.50E−05 | 9.11E−04 | LI.M4.10_cell cycle (II) | * |
377 | 97 | 11 | 3 | 7.04E−05 | 2.43E−03 | DC.M5.3_Undetermined | |
377 | 245 | 18 | 7 | 1.51E−04 | 4.97E−03 | DC.M5.5_Undetermined | |
377 | 59 | 8 | 2 | 1.98E−04 | 6.18E−03 | DC.M4.14_Monocytes | |
377 | 34 | 6 | 1 | 2.91E−04 | 8.68E−03 | DC.M7.31_Undetermined | |
377 | 14 | 4 | 0 | 4.53E−04 | 1.29E−02 | LI.M173_erythrocyte differentiation | |
377 | 26 | 5 | 1 | 6.26E−04 | 1.71E−02 | DC.M8.26_Undetermined | |
377 | 16 | 4 | 0 | 7.88E−04 | 2.07E−02 | LI.M4.9_mitotic cell cycle in stimulated CD4 T cells | * |
377 | 17 | 4 | 0 | 1.01E−03 | 2.45E−02 | LI.M19_T cell differentiation (Th2) | |
377 | 17 | 4 | 0 | 1.01E−03 | 2.45E−02 | LI.M136_TBA | |
377 | 33 | 5 | 1 | 1.93E−03 | 4.52E−02 | LI.M10.0_E2F1 targets (Q3) | |
377 | 10 | 3 | 0 | 2.14E−03 | 4.85E−02 | LI.M4.14_Rho GTPase cycle | |
377 | 11 | 3 | 0 | 2.89E−03 | 5.74E−02 | LI.M4.15_enriched in monocytes (I) | |
377 | 11 | 3 | 0 | 2.89E−03 | 5.74E−02 | LI.M12_CD28 costimulation | |
377 | 11 | 3 | 0 | 2.89E−03 | 5.74E−02 | LI.M33_inflammatory response | |
377 | 11 | 3 | 0 | 2.89E−03 | 5.74E−02 | LI.M171_heme biosynthesis (I) | |
377 | 12 | 3 | 0 | 3.77E−03 | 7.28E−02 | LI.M4.11_mitotic cell cycle in stimulated CD4 T cells | |
377 | 13 | 3 | 0 | 4.81E−03 | 9.01E−02 | LI.M15_Ran mediated mitosis |