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Table 6 The computational time (seconds) of the estimated haplotype frequencies across statistical methods and four conditions of LoDSNP (30%, 20%, 10%, 0%) and LoDMOI (15%, 10%, 5%, 0%)

From: Markov chain Monte Carlo Gibbs sampler approach for estimating haplotype frequencies among multiple malaria infected human blood samples

 

MHF

R-EM

Bayesian

EM

MCMC

Gibbs

(LoDSNP/LoDMOI)

      

 0/0

29.8

517.5

3.5

19.9

5.4

25.5

 0.10/0.05

31.1

353.6

3.4

1.9

5.2

19.2

 0.20/0.10

25.6

227.5

3.3

1.3

4.8

13.1

 0.30/0.15

23.4

127.7

3.1

0.9

4.4

8.7

  1. Lower value represents faster calculation
  2. MHF MalHaploFreq, R-EM malaria em, Bayesian Bayesian statistic, EM EM algorithm, MCMC Markov chain Monte Carlo, Gibbs Gibbs sampler, LoD limit of detection, SNP single nucleotide polymorphisms, MOI multiplicity of infection